Effective atomic number and photon buildup factor of bismuth doped tissue for photon and particles beam interaction

Abstract Introduction: The doping of high Z nanoparticles into the tumor tissue increases therapeutic efficiency radiotherapy called nanoparticle enhanced (NERT). In present study, we are identifying effective types radiation and concentration bismuth radiosensitizer for NERT application by analyzing atomic number (Zeff) photon buildup factor (PBF) (Bi) doped soft photon, electron, proton, alpha particle, carbon ion interactions. Material methods: direct method was used calculation Zeff electron beams (10 keV-30 MeV). phy-X/ZeXTRa software utilized particle such as ions (1-15 Bismuth concentrations 5, 10, 15, 20, 25 30 mg/g were considered. PBF calculated over 15 keV-15 MeV energies using phy-X/PSD software. Results: low energy (<100 keV) interaction with a higher Bi dopped gives values Zeff. increased all radiation. dependent on type radiation, doping. less has compared to beam interaction. On other hand, decreased while increasing concentration. Conclusions: According PBF, most application. Based Zeff, presented useful dosimetry in NERT.